e-Pharmalink - September 2006

News

Computer-based medical record system in rural setting
HIV/AIDS
Tuberculosis (TB)
Malaria

Focus on Resources


NEWS

Computer-based Medical Record System in rural setting

A rural health centre in Kenya with no electricity has successfully integrated a computer-based outpatient record system. The design and implementation of the system was done in collaboration with Kenya based Moi University’s Faculty of Health Sciences and US-based University of Indiana. The health centre is the sole health care provider for a community of approximately forty thousand people.
http://www.comminit.com/strategicthinking/st2006/thinking-1737.html

HIV/AIDS

WHO issues guidelines on use of cotrimoxazole prophylaxis

WHO has released guidelines on Cotrimoxazole prophylaxis. The guidelines state that Cotrimoxazole prophylaxis should be widely used by people with progressing HIV disease and by all HIV-infected or exposed infants. Once it is clear that the infants are uninfected the treatment should cease.

http://www.aidsmap.com/en/news/F49B70EE-0089-4624-8C38-82AB06A800AF.asp

The guidelines can be viewed on:
http://www.who.int/hiv/pub/guidelines/ctx/en/index.html

Side effects of commonly-used ARV drug causing concern

Commonly used ARV drug, Stavudine (also known as Zerit or d4T) is causing serious side effects which have forced medical experts to re-evaluate its use. The drug causes lactic acidosis; a rare and serious illness caused when lactic acid is not eliminated from the body and instead builds up in the blood and cells which has caused death in some reported cases.

http://www.plusnews.org/AIDSreport.asp?ReportID=6408&SelectRegion=Southern_Africa

Rapid antibody test to diagnose HIV in infants

HIV diagnosis in infants under 18 months of age is complicated because the infants retain their mothers’ antibodies for up to 18 months after birth. To distinguish between maternal and infant HIV antibodies, it is necessary to carry out direct tests for HIV using DNA PCR testing. This can only be conducted through well-equipped laboratories that can carry out viral load testing which is expensive and unavailable for most infants in resource-poor environments. Consequently two separate rapid antibody tests which can diagnose HIV infection with 95-97% accuracy in infants as young as four months are in trial in South Africa.

http://www.aidsmap.com/en/news/DAEE0A6A-109A-4D04-81C8-D88E111E0991.asp

Monitoring antiretroviral treatment with limited laboratory services

Limited laboratory services often complicate or hinder effective ART treatment. This analysis offers suggestions on how best to upgrade existing laboratory systems to efficiently cater for HIV/AIDS patients.

http://www.aidsmap.com/cms1060152.asp

TUBERCULOSIS (TB)

Action plan to combat multi-drug resistant TB (MDR TB)

Following the reports of the MDR TB in South Africa, an emergency two day Expert Consultation by global health agencies has developed an action plan to fight the strain. The focus of the plan will be to:

  • conduct rapid surveys of MDR-TB
  • enhance laboratory capacity
  • improve technical capacity of clinical and public health managers to effectively respond to MDR-TB outbreaks
  • implement infection control precautions
  • increase research support for anti-TB drug development
  • increase research support for rapid diagnostic test development
  • promote universal access to ARVS under joint TB/HIV activities

http://www.mrc.ac.za/pressreleases/2006/8pres2006.htm

Cost effectiveness of treating multi-drug resistance TB (MDR TB)

To determine the health benefits and cost-effectiveness of using drug susceptibility testing and second-line drugs in a lower-middle-income setting with high levels of MDR TB, a research was conducted in Peru. The findings on the research can be found on:

http://medicine.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pmed.0030241

MALARIA:

Anti-malarial drug to be offered for less

Coartem® the only pre-qualified fixed-dose combination therapy for malaria, shown to have cure rates of up to 95% even in areas of multi-drug resistance, will soon be offered for approximately 1 USD$ per treatment.

http://www.novartis.com/

Malaria medicines for children

WHO’s recommended list for ACT-based malaria medicines for children can be found and ordered from:

http://www.unicef.org/supply/index_23995.html#List  

FOCUS ON RESOURCES

WEBSITES:

These websites offer information on medicines for children:
The British Neonatal and Paediatric Pharmacists Group website http://www.nppg.org.uk/
The British National Formulary for Children http://bnfc.org/bnfc/

REPORTS:

WHO Treatment guidelines

The World Health Organization (WHO) has recently published new guidelines for HIV and AIDS treatment. The guidelines which include Antiretroviral drugs for treating pregnant women and preventing HIV infection in infants in resource-limited settings and Antiretroviral therapy for HIV infection in adults and adolescents in resource-limited settings can be viewed on:

http://www.who.int/hiv/pub/guidelines/en/.

WHO Report on Pharmaceutical Exports

The 40th edition report of the WHO expert committee on specifications for pharmaceutical preparations is available online at:

http://whqlibdoc.who.int/trs/who_TRS_937_eng.pdf

Service Delivery in difficult environments: A guide to key issues

This guide highlights key issues to be considered when delivering services in countries facing civil war, poverty, weak infrastructure, poor governance or other circumstances that would hinder the efficient delivery of health services.

http://www.eldis.org/healthsystems/sdde/index.htm

BOOKS

HIV and AIDS Treatment Education: A Critical Component of Efforts to Ensure Universal Access to Prevention, Treatment and Care (2006)

This book highlights the role that the education sector can play in collaboration with other sectors engaged in efforts to achieve universal access to treatment, prevention, care and support. It considers some key strategies, including how to effectively engage and prepare communities and how to involve key constituencies, in particular people with HIV and those on treatment

http://unesdoc.unesco.org/images/0014/001461/146114e.pdf  

COURSES:

Course: Tuberculosis/HIV management course
Venue: All African Leprosy and Rehabilitation Training Centre ALERT, Addis Ababa, Ethiopia.
Dates: 13th – 17th November 2006
For more information please email: monika.hoffman@dahw.de

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